| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-glucosidase MAL12 |
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| Ligand | BDBM152494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | alpha-Glucosidase Assay |
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| IC50 | 1.83e+4± 5.6e+2 nM |
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| Citation |  Rahim, F; Malik, F; Ullah, H; Wadood, A; Khan, F; Javid, MT; Taha, M; Rehman, W; Ur Rehman, A; Khan, KM Isatin based Schiff bases as inhibitors of a-glucosidase: Synthesis, characterization, in vitro evaluation and molecular docking studies. Bioorg Chem60:42-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-glucosidase MAL12 |
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| Name: | Alpha-glucosidase MAL12 |
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| Synonyms: | α-Glucosidase | MAL12 | MAL12_YEAST | MAL1S | Maltase | alpha-Glucosidase (α-Glucosidase) |
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| Type: | Protein |
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| Mol. Mass.: | 68084.32 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P53341 |
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| Residue: | 584 |
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| Sequence: | MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
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| BDBM152494 |
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| n/a |
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| Name | BDBM152494 |
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| Synonyms: | (E)-2-(2,4-dichlorophenyl)-N'-(2-oxo-1-propylindolin-3-ylidene)acetohydrazide (2) |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17Cl2N3O2 |
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| Mol. Mass. | 390.263 |
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| SMILES | CCCN1C(=O)\C(=N\NC(=O)Cc2ccc(Cl)cc2Cl)c2ccccc12 |
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| Structure | 
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