| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM152501 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Acetylcholinesterase Inhibition Assay |
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| pH | 8±n/a |
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| Ki | 4.34±0.0 nM |
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| IC50 | 4.20±0.0 nM |
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| Comments | extracted |
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| Citation |  Öztaskin, N; Çetinkaya, Y; Taslimi, P; Göksu, S; Gülçin, Ä° Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives. Bioorg Chem60:49-57 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) |
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| Type: | Enzyme |
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| Mol. Mass.: | 67792.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22303 |
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| Residue: | 614 |
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| Sequence: | MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
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| BDBM152501 |
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| n/a |
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| Name | BDBM152501 |
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| Synonyms: | (2-Bromo-4-methoxyphenyl)(2,3-dimethoxyphenyl)methanone (11) |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15BrO4 |
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| Mol. Mass. | 351.192 |
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| SMILES | COc1ccc(C(=O)c2cccc(OC)c2OC)c(Br)c1 |
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| Structure | 
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