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TargetAcetylcholinesterase
LigandBDBM152508
Substrate/Competitorn/a
Meas. Tech.Acetylcholinesterase Inhibition Assay
pH8±n/a
Ki 3.75±0.0 nM
IC50 4.84±0.0 nM
Commentsextracted
Citation Öztaskin NÇetinkaya YTaslimi PGöksu SGülçin Ä° Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives. Bioorg Chem 60:49-57 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholinesterase
Name:Cholinesterases; ACHE & BCHE
Synonyms:AChE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE)
Type:Enzyme
Mol. Mass.:67792.70
Organism:Homo sapiens (Human)
Description:n/a
Residue:614
Sequence:
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
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  Blast E-value cutoff:
BDBM152508
n/a
NameBDBM152508
Synonyms:(2-Bromo-4-hydroxyphenyl)(2,3-dihydroxyphenyl)methanone (21)
TypeSmall organic molecule
Emp. Form.C13H9BrO4
Mol. Mass.309.112
SMILESOc1ccc(C(=O)c2cccc(O)c2O)c(Br)c1
Structure
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