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TargetPeptidyl-prolyl cis-trans isomerase B
LigandBDBM50030555
Substrate/Competitorn/a
Meas. Tech.Surface Plasmon Resonance (SPR) Assay
pH7.4±n/a
Kd 0.500±n/a nM
Commentsextracted
Citation Fu, JKarur, SLi, XLu, PMergo, WRivkin, ASweeney, ZKTjandra, MWeiss, AYifru, A Cyclic peptides and use as medicines US Patent US9566312 Publication Date 2/14/2017
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase B
Name:Peptidyl-prolyl cis-trans isomerase B
Synonyms:CYP-S1 | CYPB | Cyclophilin B | Cyclophilin B (CypB) | PPIB | PPIB_HUMAN | PPIase | Peptidyl-prolyl cis-trans isomerase B | Rotamase | S-cyclophilin | SCYLP
Type:Protein
Mol. Mass.:23751.82
Organism:Homo sapiens (Human)
Description:P23284
Residue:216
Sequence:
MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRV
IFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG
ERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVR
KVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE
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  Blast E-value cutoff:
BDBM50030555
n/a
NameBDBM50030555
Synonyms:CHEMBL3344493 | US9566312, Compound 2.10
TypeSmall organic molecule
Emp. Form.C63H110N12O12
Mol. Mass.1227.6207
SMILES[H][C@@]1([C@H](C)CC#N)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](CC)NC(=O)[C@]([H])([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC1=O)C(C)C |r|
Structure
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