| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylpolyamine amidohydrolase |
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| Ligand | BDBM152730 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | APAH Fluorimetric Assay |
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| pH | 8.2±n/a |
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| IC50 | 68± 6 nM |
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| Comments | extracted |
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| Citation |  Decroos, C; Christianson, DW Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase. Biochemistry54:4692-703 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylpolyamine amidohydrolase |
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| Name: | Acetylpolyamine amidohydrolase |
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| Synonyms: | APAH_MYCRA | Acetylpolyamine amidohydrolase (APAH) | Acetylpolyamine aminohydrolase | aph | aphA |
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| Type: | Protein |
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| Mol. Mass.: | 36324.64 |
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| Organism: | Mycoplana ramosa (Gram-negative bacterium) |
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| Description: | n/a |
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| Residue: | 341 |
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| Sequence: | MRVIFSEDHKLRNAKTELYGGELVPPFEAPFRAEWILAAVKEAGFDDVVAPARHGLETVL
KVHDAGYLNFLETAWDRWKAAGYKGEAIATSFPVRRTSPRIPTDIEGQIGYYCNAAETAI
SPGTWEAALSSMASAIDGADLIAAGHKAAFSLCRPPGHHAGIDMFGGYCFINNAAVAAQR
LLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAG
AGTTANYPMGRGTPYSVWGEALTDSLKRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPD
YITMGRTIAASGVPLLVVMEGGYGVPEIGLNVANVLKGVAG
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| BDBM152730 |
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| n/a |
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| Name | BDBM152730 |
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| Synonyms: | 7-Amino-N-hydroxypentanamide (6) |
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| Type | Small organic molecule |
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| Emp. Form. | C7H17N2O2 |
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| Mol. Mass. | 161.2215 |
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| SMILES | [NH3+]CCCCCCC(=O)NO |
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| Structure | 
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