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TargetAcetylpolyamine amidohydrolase (APAH)
LigandBDBM152731
Substrate/Competitorn/a
Meas. Tech.APAH Fluorimetric Assay
pH8.2±n/a
IC50 1.5e+2± 2e+1 nM
Commentsextracted
Citation Decroos CChristianson DW Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase. Biochemistry 54:4692-703 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylpolyamine amidohydrolase (APAH)
Name:Acetylpolyamine amidohydrolase (APAH)
Synonyms:Acetylpolyamine aminohydrolase
Type:Protein
Mol. Mass.:36324.64
Organism:Mycoplana ramosa (Gram-negative bacterium)
Description:n/a
Residue:341
Sequence:
MRVIFSEDHKLRNAKTELYGGELVPPFEAPFRAEWILAAVKEAGFDDVVAPARHGLETVL
KVHDAGYLNFLETAWDRWKAAGYKGEAIATSFPVRRTSPRIPTDIEGQIGYYCNAAETAI
SPGTWEAALSSMASAIDGADLIAAGHKAAFSLCRPPGHHAGIDMFGGYCFINNAAVAAQR
LLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAG
AGTTANYPMGRGTPYSVWGEALTDSLKRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPD
YITMGRTIAASGVPLLVVMEGGYGVPEIGLNVANVLKGVAG
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  Blast E-value cutoff:
BDBM152731
n/a
NameBDBM152731
Synonyms:8-Amino-N-hydroxypentanamide (7)
TypeSmall organic molecule
Emp. Form.C8H19N2O2
Mol. Mass.175.2481
SMILES[NH3+]CCCCCCCC(=O)NO
Structure
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