Reaction Details |
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Target | Fatty acid-binding protein, intestinal |
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Ligand | BDBM50074922 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorophore Displacement Assay |
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Temperature | 566.3±0 K |
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Ki | 2.32e+4± 6.2e+3 nM |
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Citation | Patil, R; Laguerre, A; Wielens, J; Headey, SJ; Williams, ML; Hughes, ML; Mohanty, B; Porter, CJ; Scanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol9:2526-34 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Fatty acid-binding protein, intestinal |
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Name: | Fatty acid-binding protein, intestinal |
Synonyms: | FABP2 | FABPI | FABPI_HUMAN | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP | Intestinal fatty acid-binding protein (hIFABP) |
Type: | Protein |
Mol. Mass.: | 15207.56 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 132 |
Sequence: | MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
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BDBM50074922 |
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n/a |
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Name | BDBM50074922 |
Synonyms: | (+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid | 2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | 2-(2-fluorobiphenyl-4-yl)propanoic acid | 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid | 3-fluoro-4-phenylhydratropic acid | Ansaid | CHEMBL563 | FLURBIPROFEN | US9630914, Compound A |
Type | Small organic molecule |
Emp. Form. | C15H13FO2 |
Mol. Mass. | 244.2609 |
SMILES | CC(C(O)=O)c1ccc(c(F)c1)-c1ccccc1 |
Structure |
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