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TargetShort-chain Z-isoprenyl diphosphate synthase
LigandBDBM153331
Substrate/Competitorn/a
Meas. Tech.Radiometric Assay
IC50 1.90e+4±n/a nM
Citation Kim, MOFeng, XFeixas, FZhu, WLindert, SBogue, SSinko, Wde Oliveira, CRao, GOldfield, EMcCammon, JA A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery. Chem Biol Drug Des85:756-69 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Short-chain Z-isoprenyl diphosphate synthase
Name:Short-chain Z-isoprenyl diphosphate synthase
Synonyms:ZFPP_MYCBO | cis-Farnesyl diphosphate synthase (cis-FPPS)
Type:Protein
Mol. Mass.:29475.52
Organism:Mycobacterium tuberculosis H37Rv
Description:Q7U0P8
Residue:262
Sequence:
MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDGNRRWARSAGYDDVSYGYRM
GAAKIAEMLRWCHEAGIELATVYLLSTENLQRDPDELAALIEIITDVVEEICAPANHWSV
RTVGDLGLIGEEPARRLRGAVESTPEVASFHVNVAVGYGGRREIVDAVRALLSKELANGA
TAEELVDAVTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHWPA
FRHVDFLRALRDYSARHRRYGR
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BDBM153331
n/a
NameBDBM153331
Synonyms:BPH-1427
TypeSmall organic molecule
Emp. Form.C26H24N2
Mol. Mass.364.4822
SMILESNCCc1cccc(c1)C#Cc1ccc(cc1)C#Cc1cccc(CCN)c1
Structure
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