| Reaction Details |
|---|
 | Report a problem with these data |
| Target | VIM-24 |
|---|
| Ligand | BDBM153700 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Direct Competition Assay |
|---|
| Ki | 4.9e+3± 3e+2 nM |
|---|
| Citation |  Mojica, MF; Mahler, SG; Bethel, CR; Taracila, MA; Kosmopoulou, M; Papp-Wallace, KM; Llarrull, LI; Wilson, BM; Marshall, SH; Wallace, CJ; Villegas, MV; Harris, ME; Vila, AJ; Spencer, J; Bonomo, RA Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-ß-lactamases. Biochemistry54:3183-96 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| VIM-24 |
|---|
| Name: | VIM-24 |
|---|
| Synonyms: | Metallo-beta-lactamase VIM-24 (VIM-24) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 28273.97 |
|---|
| Organism: | Klebsiella pneumoniae (Enterobacteria) |
|---|
| Description: | E0AFT6 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSLTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
|
|
|
|---|
| BDBM153700 |
|---|
| n/a |
|---|
| Name | BDBM153700 |
|---|
| Synonyms: | L-VC26 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H15NO2S3 |
|---|
| Mol. Mass. | 265.416 |
|---|
| SMILES | CC1(C)S[C@H]2CS[C@H](CS)N2[C@@H]1C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
