| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase |
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| Ligand | BDBM20607 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Exogenous PldA Assay |
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| pH | 7.5±n/a |
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| IC50 | 15000±260 nM |
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| Comments | extracted |
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| Citation |  Scott, SA; Spencer, CT; O'Reilly, MC; Brown, KA; Lavieri, RR; Cho, CH; Jung, DI; Larock, RC; Brown, HA; Lindsley, CW Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes. ACS Chem Biol10:421-32 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase |
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| Name: | Phospholipase |
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| Synonyms: | Phospholipase D (PldA) |
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| Type: | Protein |
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| Mol. Mass.: | 122309.70 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | A0A0C6EPQ5 |
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| Residue: | 1099 |
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| Sequence: | MLQKKPYNGLHEKELNQINQQDGSPCVAISAPGCFIKGSNLFSEKRAGNRVRFFTTGRDY
FSDLASALDSASSSIFITGWQVNYDVLLDGRRSLWQCLRQALERSPALKVYVMPWLSPSG
SLGTYDFETMLAVFQLNAGLEGGARAFCTPAIQQSDMQGLGVAFSHHQKSVVIDNRIGYV
GGIDLAYGRRDDNDFSLDASGRRGNDAYNPGLPHLGWMAEDEHVSSMGLMMATLFDLSRP
LASLTLHAPTLRLSPFPHIAASDEPLLSIPLAPSRARALNGGAYLSDLFRSPMLPSLQWL
GRAYNSSKEGLDEGFERLDALRRQMVASSIRAIANLIADNLDALPIEPELERRLRAWLEE
LRTAALNLPEALRIKSLLLINQWMSETELGQVLTLISGKGFEDIPQNLSGKAGELAGSLF
WTLHRLLQARAGGHQQPYRYLDEAPQPLASPDNARLAADQPRMPWQDVHCRIEGPSVYDL
ARNFIDRWNGQQAYLAKTPALQDTALVRSALEAVMKWLNSLAAAAGLENYLDEKRNLRLE
LDPPTPCWINAPEQLPQEPEVRRGGMTVQVLRSAAARMLEQEQAGRLGAGVNLPLQVGVS
TEGVQSNCKDAMLLAISGAQQFIYIENQFFQSEFGKEGEVFKDLPLSGPMASLRDVGSLR
RDFVVRIRLEEALEQRDLWLLDWAEVEKIAQEPGTEARQFLKSMLAMWGVNAQGWLTHKL
GEAQHGLLNEIGEALARRIERAIQREHPFHVYLVLPVHPEGALNVPNIMHQVHLTQQSLV
FGEQSLVKRIQRQMALKALEGKSDPAQAREIIERKDARGRPVYEQQDWSRYLTLLNLRTW
AVLGGRVVTEQIYVHSKLLIADDRVAILGSANINDRSLQGERDSELAVMVRDSEPLTVRL
DGKNDAIVGKAIHQLRVNLWKKHFGLSQGPGGFVKPASELSAYLSIPAAQEAWEAIQTLA
KENTRAYERTFNFIPQNISQTQLQLTPEPPKGFEDGFPASIWPTWAYRKPGELRAGGQLM
EPMPYQEIFWRSSNLTSVKTFPPPNGVSGFITALPTSWTRGERNDSGLNLSILAHQDSRS
LPTQVAMNGDSSAQGKHRT
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| BDBM20607 |
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| n/a |
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| Name | BDBM20607 |
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| Synonyms: | (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine | 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine | CHEMBL83 | FOSTRIECIN SODIUM | NCGC00024928 | Nolvadex | Tamoxifen | Tamoxifen (8) | Tamoxifen, 7 | cid_2733526 | med.21724, Compound Tamoxifen |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29NO |
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| Mol. Mass. | 371.5146 |
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| SMILES | CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 |
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| Structure | 
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