| Reaction Details |
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 | Report a problem with these data |
| Target | C-terminal-binding protein 1 |
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| Ligand | BDBM154570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CtBP2 ITC |
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| pH | 7.5±0 |
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| Kd | 3.7e+2± 3e+1 nM |
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| Citation |  Hilbert, BJ; Morris, BL; Ellis, KC; Paulsen, JL; Schiffer, CA; Grossman, SR; Royer, WE Structure-guided design of a high affinity inhibitor to human CtBP. ACS Chem Biol10:1118-27 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-terminal-binding protein 1 |
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| Name: | C-terminal-binding protein 1 |
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| Synonyms: | C-terminal binding protein (CtBP1) | C-terminal-binding protein 1 (CtBP1) | CTBP | CTBP1 | CTBP1_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 47537.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13363 |
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| Residue: | 440 |
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| Sequence: | MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQ
EIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNV
PAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGII
GLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLN
EHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFS
QGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAAT
HWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA
PSPGQTVKPEADRDHASDQL
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| BDBM154570 |
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| n/a |
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| Name | BDBM154570 |
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| Synonyms: | 2-Hydroxyimino-3-phenylpropanoic acid (HIPP) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9NO3 |
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| Mol. Mass. | 179.1727 |
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| SMILES | ON=C(Cc1ccccc1)C(O)=O |w:1.0| |
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| Structure | 
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