| Reaction Details |
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 | Report a problem with these data |
| Target | Methyl-CpG-binding domain protein 2 |
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| Ligand | BDBM158511 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| IC50 | 210±n/a nM |
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| Citation |  Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z Agents for reversing epigenetic silencing of genes US Patent US9034574 Publication Date 5/19/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Methyl-CpG-binding domain protein 2 |
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| Name: | Methyl-CpG-binding domain protein 2 |
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| Synonyms: | MBD2 | MBD2_HUMAN | Methyl-CpG binding domain protein 2 | Methyl-CpG-binding domain protein 2 (MBD2) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43278.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21595776 |
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| Residue: | 411 |
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| Sequence: | MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN
TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII
KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK
AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA
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| BDBM158511 |
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| n/a |
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| Name | BDBM158511 |
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| Synonyms: | US9034574, XXI |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11ClN2S |
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| Mol. Mass. | 274.769 |
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| SMILES | Clc1ccc(cc1)C1NN=C(S1)c1ccccc1 |c:10| |
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| Structure | 
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