| Reaction Details |
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 | Report a problem with these data |
| Target | 2-acylglycerol O-acyltransferase 2 |
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| Ligand | BDBM159700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 45±n/a nM |
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| Citation |  Busujima, T; Oi, T; Tanaka, H; Shirasaki, Y; Iwakiri, K; Sato, N; Tokita, S Nitrogen-containing condensed heterocyclic compound US Patent US9035059 Publication Date 5/19/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-acylglycerol O-acyltransferase 2 |
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| Name: | 2-acylglycerol O-acyltransferase 2 |
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| Synonyms: | 2-acylglycerol O-acyltransferase 2 | Acyl-CoA:monoacylglycerol acyltransferase 2 | Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) | DC5 | DGAT2L5 | Diacylglycerol O-acyltransferase candidate 5 | Diacylglycerol acyltransferase 2-like protein 5 | MGAT2 | MOGAT2 | MOGT2_HUMAN | Monoacylglycerol Acyltransferase 2 (MGAT2) | Monoacylglycerol O-acyltransferase 2 | hDC5 | hMGAT2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 38210.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q3SYC2 |
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| Residue: | 334 |
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| Sequence: | MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLD
RDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFAN
LCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNL
LGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG
SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEE
VNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC
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| BDBM159700 |
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| n/a |
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| Name | BDBM159700 |
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| Synonyms: | US9035059, 17-2 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H47FN2O3S |
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| Mol. Mass. | 594.823 |
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| SMILES | CCCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(CCc4ccc(cc4)C(C)(C)C)CCc3c2)c(F)c1 |
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| Structure | 
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