Reaction Details | |||
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Target | Gonadotropin-releasing hormone receptor | ||
Ligand | BDBM160321 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | FLIPR Calcium Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 2±n/a nM | ||
Comments | extracted | ||
Citation | Ohno, K; Miyagi, T; Ozawa, T; Fushimi, N Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof US Patent US9040693 Publication Date 5/26/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Gonadotropin-releasing hormone receptor | |||
Name: | Gonadotropin-releasing hormone receptor | ||
Synonyms: | GNRHR | GNRHR_HUMAN | GRHR | GnRH receptor | GnRH-R | Gonadotropin releasing hormone 1 (GnRHR1) | Gonadotropin-releasing hormone receptor | Gonadotropin-releasing hormone receptor (GnRH) | ||
Type: | Enzyme | ||
Mol. Mass.: | 37749.45 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P30968 | ||
Residue: | 328 | ||
Sequence: |
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BDBM160321 | |||
n/a | |||
Name | BDBM160321 | ||
Synonyms: | US9040693, 22 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H16ClN3O6S2 | ||
Mol. Mass. | 517.962 | ||
SMILES | OC(=O)c1scc2[nH]c(=O)n(-c3cc(ccc3Cl)S(=O)(=O)N3CCCc4ccccc34)c(=O)c12 |(-8.56,-1.78,;-7.02,-1.78,;-6.25,-3.11,;-6.25,-.44,;-7.15,.8,;-6.25,2.05,;-4.78,1.57,;-3.45,2.34,;-2.11,1.57,;-.78,2.34,;-2.11,.03,;-.78,-.74,;.55,.03,;1.89,-.74,;1.89,-2.28,;.55,-3.05,;-.78,-2.28,;-2.11,-3.05,;3.22,.03,;2.45,1.37,;3.99,-1.3,;4.55,.8,;4.55,2.34,;5.89,3.11,;7.22,2.34,;7.22,.8,;8.56,.03,;8.56,-1.51,;7.22,-2.28,;5.89,-1.51,;5.89,.03,;-3.45,-.74,;-3.45,-2.28,;-4.78,.03,)| | ||
Structure |