| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pro-glucagon |
|---|
| Ligand | BDBM160577 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 277.15±n/a K |
|---|
| Ki | 38±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Chakravarty, D; Greco, M; Shook, B; Xu, G; Zhang, R Biphenyl derivatives useful as glucagon receptor antagonists US Patent US9045389 Publication Date 6/2/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pro-glucagon |
|---|
| Name: | Pro-glucagon |
|---|
| Synonyms: | GCG | GLUC_HUMAN | Glucagon | Glucagon receptor (GCGR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 20907.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P01275 |
|---|
| Residue: | 180 |
|---|
| Sequence: | MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTS
DYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
AWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
|
|
|
|---|
| BDBM160577 |
|---|
| n/a |
|---|
| Name | BDBM160577 |
|---|
| Synonyms: | US9045389, 9 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H24FN3O5 |
|---|
| Mol. Mass. | 513.5164 |
|---|
| SMILES | OC(=O)CCNC(=O)c1ccc(cc1)-c1ccccc1CNc1ccc(cc1)-c1ccc(F)c(c1)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
