Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | D(1A) dopamine receptor | ||
Ligand | BDBM160876 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Competition Binding Assay | ||
Ki | 7.66±n/a nM | ||
Citation | Brodney, MA; Davoren, JE; Dounay, AB; Efremov, IV; Gray, DL; Green, ME; Henderson, JL; Lee, C; Mente, SR; O'Neil, SV; Rogers, BN; Zhang, L Heteroaromatic compounds and their use as dopamine D1 ligands US Patent US9107923 Publication Date 8/18/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
D(1A) dopamine receptor | |||
Name: | D(1A) dopamine receptor | ||
Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | ||
Type: | Enzyme | ||
Mol. Mass.: | 49303.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P21728 | ||
Residue: | 446 | ||
Sequence: |
| ||
BDBM160876 | |||
n/a | |||
Name | BDBM160876 | ||
Synonyms: | US10093655, Example 46 | US11014909, Example 46 | US9107923, 46 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H21N3O2 | ||
Mol. Mass. | 347.4103 | ||
SMILES | Cc1cc(Oc2ncccc2C2CC2)ccc1-c1c(C)n[nH]c(=O)c1C |(.77,3.47,;.77,1.93,;-.56,1.15,;-.56,-.38,;-1.9,-1.15,;-1.9,-2.69,;-.56,-3.47,;-.56,-5,;-1.9,-5.78,;-3.23,-5,;-3.23,-3.47,;-4.56,-2.69,;-5.33,-1.36,;-6.1,-2.69,;.77,-1.15,;2.1,-.38,;2.1,1.15,;3.44,1.93,;4.77,1.15,;4.77,-.38,;6.1,1.93,;6.1,3.47,;4.77,4.23,;4.77,5.78,;3.44,3.47,;2.1,4.23,)| | ||
Structure |