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TargetBifunctional ligase/repressor BirA
LigandBDBM161470
Substrate/Competitorn/a
Meas. Tech.Enzyme Inhibition Assay
pH8±n/a
Temperature310.15±n/a K
Ki>30000±n/a nM
Commentsextracted
Citation Abell, APolyak, SBooker, GWallace, JSoares da Costa, TJarrad, ATieu, WKeeling, KLPedersen, DSPendini, NWilce, MYap, MY Antimicrobial compounds US Patent US9108978 Publication Date 8/18/2015
More Info.:Get all data from this article,  Assay Method
 
Bifunctional ligase/repressor BirA
Name:Bifunctional ligase/repressor BirA
Synonyms:BIRA_ECOLI | Biotin operon repressor | Biotin protein ligase (BPL) | Biotin--[acetyl-CoA-carboxylase] synthetase | BirA Bifunctional Protein | bioR | birA | dhbB
Type:Repressor protein
Mol. Mass.:35313.58
Organism:Escherichia coli
Description:n/a
Residue:321
Sequence:
MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL
PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG
RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ
DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA
MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL
EQDGIIKPWMGGEISLRSAEK
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  Blast E-value cutoff:
BDBM161470
n/a
NameBDBM161470
Synonyms:US9108978, 4.01
TypeSmall organic molecule
Emp. Form.C21H30N10OS
Mol. Mass.470.594
SMILESNc1ncnc2n(CCCCn3cc(CCCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)cnc12 |r|
Structure
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