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TargetTyrosine-protein kinase Fgr
LigandBDBM50430875
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
pH8±n/a
IC50 3.7±n/a nM
Commentsextracted
Citation Yang BKim YPark TWoo SLee HKim SCho JLee H Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases and pharmaceutical composition containing same US Patent  US9062066 Publication Date 6/23/2015
More Info.:Get all data from this article,  Assay Method
 
Tyrosine-protein kinase Fgr
Name:Tyrosine-protein kinase Fgr
Synonyms:FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | Proto-oncogene c-Fgr | SRC2 | p55-Fgr | p58-Fgr | p58c-Fgr
Type:protein
Mol. Mass.:59469.88
Organism:Homo sapiens (Human)
Description:P09769
Residue:529
Sequence:
MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQA
INPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSL
SSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAY
SLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAP
CTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSP
KAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLV
DMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKF
PIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCP
PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT
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  Blast E-value cutoff:
BDBM50430875
n/a
NameBDBM50430875
Synonyms:CHEMBL2336005 | US9062066, LCB 03-0110
TypeSmall organic molecule
Emp. Form.C24H23N3O2S
Mol. Mass.417.523
SMILESOc1cccc(Nc2ccnc3cc(sc23)-c2cccc(CN3CCOCC3)c2)c1
Structure
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