| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 9 |
|---|
| Ligand | BDBM164883 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Kinase Inhibition Assay |
|---|
| pH | 7.5±n/a |
|---|
| IC50 | 3±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Zeitlmann, L; Niestroj, A; Heiser, U Inhibitors of protein kinases US Patent US9067888 Publication Date 6/30/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 9 |
|---|
| Name: | Cyclin-dependent kinase 9 |
|---|
| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 42789.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 372 |
|---|
| Sequence: | MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF
|
|
|
|---|
| BDBM164883 |
|---|
| n/a |
|---|
| Name | BDBM164883 |
|---|
| Synonyms: | US9067888, 33 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24FN3O3 |
|---|
| Mol. Mass. | 385.432 |
|---|
| SMILES | COc1cc(F)ccc1-c1ccnc(NC(=O)[C@H]2CCC[C@H](C2)NC(C)=O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
