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TargetComplement factor D
LigandBDBM171314
Substrate/Competitorn/a
Meas. Tech.In Vitro Assay
pH7.5±n/a
Temperature298.15±n/a K
IC50 4±n/a nM
Commentsextracted
Citation Altmann, EHommel, ULorthiois, ELMaibaum, JKOstermann, NQuancard, JRandl, SARogel, OSimic, OVulpetti, A Complement pathway modulators and uses thereof US Patent US9085555 Publication Date 7/21/2015
More Info.:Get all data from this article,  Assay Method
 
Complement factor D
Name:Complement factor D
Synonyms:Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D
Type:Protein
Mol. Mass.:27039.19
Organism:Homo sapiens (Human)
Description:P00746
Residue:253
Sequence:
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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BDBM171314
n/a
NameBDBM171314
Synonyms:US9085555, 744
TypeSmall organic molecule
Emp. Form.C22H21BrN6O3
Mol. Mass.497.345
SMILESC[C@]12C[C@H]1N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(N)=O)c2ccccc12 |r|
Structure
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