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TargetCasein kinase I isoform epsilon
LigandBDBM173195
Substrate/Competitorn/a
Meas. Tech.HTS Assay
Temperature298.15±n/a K
IC50>30000±n/a nM
Commentsextracted
Citation Wagner, FFPan, JQDandapani, SGermain, AHolson, EMunoz, BNag, PPWeiwer, MLewis, MCHaggarty, SJBishop, JAStegmaier, KBanerji, V Kinase inhibitors and methods of use thereof US Patent US9096594 Publication Date 8/4/2015
More Info.:Get all data from this article,  Assay Method
 
Casein kinase I isoform epsilon
Name:Casein kinase I isoform epsilon
Synonyms:Axin-1/Casein kinase I epsilon | CKI-epsilon | CKIe | CSNK1E | Casein kinase 1 epsilon (CK1Ɛ) | Casein kinase I epsilon | Casein kinase I isoform epsilon (CK1 epsilon) | Casein kinase I isoform epsilon (CK1E) | Casein kinase I isoform epsilon (CK1epsilon) | KC1E_HUMAN
Type:Protein
Mol. Mass.:47340.25
Organism:Homo sapiens (Human)
Description:P49674
Residue:416
Sequence:
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
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BDBM173195
n/a
NameBDBM173195
Synonyms:US10137122, Compound 3 | US9096594, 3
TypeSmall organic molecule
Emp. Form.C19H21N3O
Mol. Mass.307.3895
SMILESCc1[nH]nc2NC3=C([C@H](c12)c1ccccc1)C(=O)CC(C)(C)C3 |r,c:6|
Structure
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