Reaction Details |
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Target | Ribonuclease pancreatic |
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Ligand | BDBM173608 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Ribonuclease Activity Assay |
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Temperature | 303.15±n/a K |
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Ki | 1.591e+5± 2.69e+4 nM |
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Comments | extracted |
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Citation | Chatzileontiadou, DS; Parmenopoulou, V; Manta, S; Kantsadi, AL; Kylindri, P; Griniezaki, M; Kontopoulou, F; Telopoulou, A; Prokova, H; Panagopoulos, D; Boix, E; Balatsos, NA; Komiotis, D; Leonidas, DD Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin. Bioorg Chem63:152-65 (2015) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Ribonuclease pancreatic |
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Name: | Ribonuclease pancreatic |
Synonyms: | CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1 |
Type: | Enzyme |
Mol. Mass.: | 16468.79 |
Organism: | Bison bison (American bison) |
Description: | carboxamidomethylated RNase A |
Residue: | 150 |
Sequence: | MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRN
LTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPN
CAYKTTQANKHIIVACEGNPYVPVHFDASV
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BDBM173608 |
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n/a |
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Name | BDBM173608 |
Synonyms: | 1-[3'-[4-[(Adenine-9-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]uracil (5a) |
Type | Small organic molecule |
Emp. Form. | C17H18N10O5 |
Mol. Mass. | 442.3888 |
SMILES | Nc1ncnc2n(Cc3cn(nn3)[C@H]3[C@@H](CO)O[C@H](C3O)n3ccc(=O)[nH]c3=O)cnc12 |r| |
Structure |
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