| Reaction Details |
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 | Report a problem with these data |
| Target | Aldehyde oxidase 1 |
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| Ligand | BDBM175348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AO Enzyme Assay |
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| pH | 7±n/a |
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| Ki | 1.60e+5± 1.98e+4 nM |
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| IC50 | 1.15e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Siah, M; Farzaei, MH; Ashrafi-Kooshk, MR; Adibi, H; Arab, SS; Rashidi, MR; Khodarahmi, R Inhibition of guinea pig aldehyde oxidase activity by different flavonoid compounds: An in vitro study. Bioorg Chem64:74-84 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldehyde oxidase 1 |
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| Name: | Aldehyde oxidase 1 |
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| Synonyms: | AO | AOX1 | AOXA_CAVPO | Aldehyde oxidase (AO) | Aldehyde: O2 oxidoreductase |
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| Type: | Protein |
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| Mol. Mass.: | 145280.02 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | H9TB17 |
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| Residue: | 1332 |
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| Sequence: | MEPSTLYFYVNGRRVTEKNVDPETMLLPYLGRNLRLTGTKYGCGGGGCGACTVMVSRYDR
GTGQIRHYPACACLTPLCSLHGAAVTTVEGVGSTRTRLHPVQERIAKSHGTQCGFCTPGM
VMSLYALLRSHPQPSEEQLLEALAGNLCRCTGYRPILDAGKTFCKTSGCCQSKENGVCCL
DQGVNGVQEAEGEQTSQELCSEEEFVPLDPTQELIFPPELMILAQKQPQKSRVFTGDRVT
WISPVTLKDLLEAKAKNPRAPVVMGNTSVGPEMKFKGVFHPVIISPDGIEELSVIKQGNE
GLTLGAGLSLAQVQDVLADVVQQLPEEKTQTLCALLKQLRTLAGSQIRNMASLGGHIMSR
HLDSDLNPVLAAASCTLHVPSQEGDRQIPLDEHFLSRSPSADLRPQEVLLSVTIPYSRKW
EFVSAFRQAQRKRSARAIVNVGMRVFFGAGDGVISELCILYGGVGPAIVCATDACRKLVG
RHWTEEMLDEACRLVLGEVAIPGAAPGGRVEFRRTLLVSFLFRFYLQVSQSLSRMDPGRY
PSLVGKYESALEDLCLGHHQRTFELQSADAKQLPQDPIGRPIMHLSGIKHTTGEAIYCDD
MPLVDRELSLAFVTSSRAHAAILSMDLSEALSLPGVVDIVTAEHLGDANSFAKETLLATD
KVLCVGHLVCAVIADSEVQAKRAAEKVKIVYQDLEPLILTIEEAIQHDSFFETERKLESG
DVAEAFRTAEQVLEGSIHMGGQEHFYMETQSMLAVPKGEDQEIDLYVSTQFPTYIQEIVA
STLKLPVNKVMCHVRRVGGAFGGKVGKTAILAAITAFAALKHCRAVRCILERGEDMLITG
GRHPYLGKYKVGFRNNGQVVALDMEHYSNAGSTLDESLMVVEMGLLKMENAYKFPNLRCR
GHACKTNLPSNTALRGFGFPQSGLITEACIVEVAARCGLSPEEVREVNMYRGTEQTHYGQ
EIHTQRLAQCWSECKAKATFSLRRAAVDRFNAGSPWKKRGLAMVPLKFPVGLGSVAMGQA
AALVHVYLDGSVLLTHGGIEMGQGVHTKMIQVVSRELKMPMANVHLRGTSTETVPNANVS
GGSVVADLNGLAVKDACQTLLKRLEPIISKNPKGTWKEWAQAAFDQSISLSAIGYFRGYD
ADMDWEKGKGHPFEYFVYGAACSEVEIDCLTGNHKNIRTDIVMDVGRSINPALDLGQVEG
AFIQGMGLYTSEELKYGPQGALYTRGPDQYKIPAVCDVPAELHVFFLPPSKNSNTLYSSK
GLGESGVFLGCSVLFAIWDAVSAARRERGLPGTLALSCPLTPEKIRMACEDRFTKMIPRD
TPGSYVPWDVVV
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| BDBM175348 |
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| n/a |
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| Name | BDBM175348 |
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| Synonyms: | 2',5'-di-Hydroxy Benzofuranone (2',5'-(OH)2) | 6-Hydroxy-2-(2',5'-dihydroxybenzylidene)benzofuran-3(2H) one |
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| Type | Small organic molecule |
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| Emp. Form. | C8H6O4 |
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| Mol. Mass. | 166.1308 |
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| SMILES | OC1Oc2ccc(O)cc2C1=O |
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| Structure | 
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