| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM5272 |
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| Substrate/Competitor | BDBM4702 |
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| Meas. Tech. | Neuraminidase Inhibition Assay |
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| pH | 6.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 3000±n/a nM |
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| Citation |  Atigadda, VR; Brouillette, WJ; Duarte, F; Babu, YS; Bantia, S; Chand, P; Chu, N; Montgomery, JA; Walsh, DA; Sudbeck, E; Finley, J; Air, GM; Luo, M; Laver, GW Hydrophobic benzoic acids as inhibitors of influenza neuraminidase. Bioorg Med Chem7:2487-97 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I75A5 | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 52468.81 |
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| Organism: | Influenza A virus (N9) |
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| Description: | P03472 |
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| Residue: | 470 |
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| Sequence: | MNPNQKILCTSATALVIGTIAVLIGITNLGLNIGLHLKPSCNCSHSQPEATNASQTIINN
YYNDTNITQISNTNIQVEERAIRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTRE
PYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGW
SSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCP
VVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGS
NRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVN
TWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECY
RACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
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| BDBM5272 |
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| BDBM4702 |
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| Name | BDBM5272 |
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| Synonyms: | 3-carbamimidamido-4-acetamido-5-(pentan-3-yloxy)benzoic acid | 4-(N-Acetylamino)-5-guanidino-3-(3-pentyloxy)benzoic acid | Benzoic Acid Inhibitor 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N4O4 |
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| Mol. Mass. | 322.3596 |
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| SMILES | [#6]-[#6]-[#6](-[#6]-[#6])-[#8]-c1cc(cc(\[#7]=[#6](/[#7])-[#7])c1-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O |
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| Structure | 
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