| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM5266 |
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| Substrate/Competitor | BDBM4702 |
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| Meas. Tech. | Neuraminidase Inhibition Assay |
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| pH | 6.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 500±n/a nM |
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| Citation |  Atigadda, VR; Brouillette, WJ; Duarte, F; Babu, YS; Bantia, S; Chand, P; Chu, N; Montgomery, JA; Walsh, DA; Sudbeck, E; Finley, J; Air, GM; Luo, M; Laver, GW Hydrophobic benzoic acids as inhibitors of influenza neuraminidase. Bioorg Med Chem7:2487-97 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza B Virus Neuraminidase | NA | NRAM_INBLE | Neuraminidase | Neuraminidase B |
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| Type: | Enzyme |
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| Mol. Mass.: | 51446.67 |
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| Organism: | Influenza B virus (B/Lee/40) |
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| Description: | n/a |
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| Residue: | 466 |
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| Sequence: | MLPSTVQTLTLLLTSGGVLLSLYVSASLSYLLYSDVLLKFSSTKTTAPTMSLECTNASNA
QTVNHSATKEMTFPPPEPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFV
ACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGS
ACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMI
TDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKR
PFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASK
IGRWYSRTMSKTNRMGMELYVKYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKC
DVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
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| BDBM5266 |
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| BDBM4702 |
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| Name | BDBM5266 |
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| Synonyms: | (2S,3S,4R)-4-carbamimidamido-2-(dipropylcarbamoyl)-3-acetamido-3,4-dihydro-2H-pyran-6-carboxylic acid | Benzoic Acid Inhibitor 4a |
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| Type | Small organic molecule |
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| Emp. Form. | C16H27N5O5 |
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| Mol. Mass. | 369.4161 |
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| SMILES | [#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#6])-[#6](=O)-[#6@H]-1-[#8]-[#6](=[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6@@H]-1-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O |r,c:11| |
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| Structure | 
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