| Reaction Details |
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 | Report a problem with these data |
| Target | Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
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| Ligand | BDBM176591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| pH | 7.4±n/a |
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| IC50 | 5750±n/a nM |
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| Comments | extracted |
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| Citation |  Holmes, IP; Bergman, Y; Lunniss, GE; Nikac, M; Chol, N; Hemley, CF; Walker, SR; Foitzik, RC; Ganame, D; Lessene, R Selective FAK inhibitors US Patent US9120761 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
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| Name: | Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
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| Synonyms: | FLT4 | VEGFR3 | VGFR3_HUMAN | modified VEGFR3 cytoplasmic domain |
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| Type: | n/a |
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| Mol. Mass.: | 34324.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35916[818-948,1003-1077] |
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| Residue: | 306 |
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| Sequence: | DPGEVPLEEQCEYLSYDASQWEFPRERLHLGRVLGYGAFGKVVEASAFGIHKGSSCDTVA
VKMLKEGATASEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCKYGNLSN
FLRAKRDAFSPDLWLSPLTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVV
KICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLG
ASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGD
LLQGRG
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| BDBM176591 |
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| n/a |
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| Name | BDBM176591 |
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| Synonyms: | US9120761, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28F3N5O2 |
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| Mol. Mass. | 499.528 |
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| SMILES | COc1cc(ccc1Nc1ncc(c(CCc2cccc(c2)C(N)=O)n1)C(F)(F)F)C1CCNCC1 |
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| Structure | 
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