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TargetPurinergic receptor P2Y1
LigandBDBM50015280
Substrate/Competitorn/a
Meas. Tech.Scintillation Proximity Assay (SPA) Assay
pH7.4±n/a
Temperature298.15±n/a K
IC50 66±n/a nM
Commentsextracted
Citation Qiao JXHu CHThibeault C Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor US Patent  US9120798 Publication Date 9/1/2015
More Info.:Get all data from this article,  Assay Method
 
Purinergic receptor P2Y1
Name:Purinergic receptor P2Y1
Synonyms:ATP receptor | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor
Type:Enzyme
Mol. Mass.:42090.25
Organism:Homo sapiens (Human)
Description:P47900
Residue:373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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  Blast E-value cutoff:
BDBM50015280
n/a
NameBDBM50015280
Synonyms:CHEMBL3263060 | US9120798, 38
TypeSmall organic molecule
Emp. Form.C32H35ClN4O2
Mol. Mass.543.099
SMILESCC(C)(C)CN1CCC2(CN(c3c2c(Cl)ccc3O)c2ccccc2Nc2cc(on2)-c2ccccc2)CC1
Structure
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