| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50015289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay (SPA) Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 8±n/a nM |
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| Comments | extracted |
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| Citation |  Qiao, JX; Hu, CH; Thibeault, C Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor US Patent US9120798 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50015289 |
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| n/a |
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| Name | BDBM50015289 |
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| Synonyms: | CHEMBL3263069 | US9120798, 44 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H45N5O3S |
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| Mol. Mass. | 639.85 |
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| SMILES | COC(=O)c1ccc(O)c2N(CC3(CCN(CC(C)(C)C)CC3)c12)c1ccccc1Nc1nnc(s1)-c1ccc(cc1)C(C)(C)C |
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| Structure | 
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