| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM178010 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | alpha-Glucosidase Inhibition Assay |
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| pH | 6.8±n/a |
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| IC50 | 3.49e+3± 5e+1 nM |
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| Comments | extracted |
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| Citation |  Imran, S; Taha, M; Ismail, NH; Kashif, SM; Rahim, F; Jamil, W; Wahab, H; Khan, KM Synthesis, In vitro and Docking Studies of New Flavone Ethers as a-Glucosidase Inhibitors. Chem Biol Drug Des87:361-73 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM178010 |
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| n/a |
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| Name | BDBM178010 |
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| Synonyms: | 2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4-one (13) |
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| Type | Small organic molecule |
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| Emp. Form. | C22H14F2O3 |
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| Mol. Mass. | 364.3416 |
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| SMILES | Fc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1F |
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| Structure | 
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