| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase SHV-1 |
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| Ligand | BDBM50021954 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cell Free Inhibition Assay |
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| pH | 7±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 3915±n/a nM |
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| Comments | extracted |
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| Citation |  Bulusu, AR Substituted clavulanic acid US Patent US9120808 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase SHV-1 |
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| Name: | Beta-lactamase SHV-1 |
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| Synonyms: | BLA1_ECOLX | Beta-lactamase (SHV-1) | bla | shv1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 31226.68 |
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| Organism: | Escherichia coli |
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| Description: | P0AD63 |
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| Residue: | 286 |
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| Sequence: | MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE
RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA
AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA
SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG
IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
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| BDBM50021954 |
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| n/a |
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| Name | BDBM50021954 |
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| Synonyms: | (2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (S)-3,3-Dimethyl-7-(R)-oxo-4,4-dioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (Sulbactam) | CHEMBL403 | CP-45,899 | SULBACTAM | UNASYN | US20230322715, Compound ALK-09 | US9120808, Sulbactam sodium salt |
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| Type | Small organic molecule |
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| Emp. Form. | C8H11NO5S |
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| Mol. Mass. | 233.242 |
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| SMILES | CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |r| |
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| Structure | 
|
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