| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM60585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Assay for α-Glucosidase Inhibitory Activity |
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| IC50 | 165.01±1.28 nM |
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| Citation |  Taha, M; Ismail, NH; Imran, S; Mohamad, MH; Wadood, A; Rahim, F; Saad, SM; Rehman, AU; Khan, KM Synthesis, a-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles. Bioorg Chem65:100-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM60585 |
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| n/a |
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| Name | BDBM60585 |
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| Synonyms: | 2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole (9) |
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| Type | n/a |
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| Emp. Form. | C14H11FN2 |
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| Mol. Mass. | 226.2489 |
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| SMILES | Cc1cccc2nc([nH]c12)-c1cccc(F)c1 |
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| Structure | 
|
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