Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM179904 |
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Substrate/Competitor | n/a |
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Meas. Tech. | n/a |
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pH | 7.5±n/a |
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Temperature | 298.15±n/a K |
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Ki | 0.05±n/a nM |
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IC50 | 58±n/a nM |
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Comments | extracted |
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Citation | Blumberg, LC; Deaver, D; Eyerman, D Morphan and morphinan analogues, and methods of use US Patent US9133125 Publication Date 9/15/2015 |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44789.51 |
Organism: | Homo sapiens (Human) |
Description: | P35372 |
Residue: | 400 |
Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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BDBM179904 |
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n/a |
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Name | BDBM179904 |
Synonyms: | US10231963, Table C.8 | US10287250, Compound D.8 | US10736890, Compound TABLE C.8 | US10752592, Compound TABLE D.8 | US11534436, Compound Table C.8 | US9133125, Table D, Compound 8 | US9656961, Example 00172 |
Type | Small organic molecule |
Emp. Form. | C20H28N2O2 |
Mol. Mass. | 328.4485 |
SMILES | C[C@H]1[C@H]2Cc3ccc(cc3[C@@]1(C)CCN2C[C@H]1CCCO1)C(N)=O |r,TLB:15:14:1:9.4.3| |
Structure |
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