| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM179877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Functional Assay (GTPgammaS Binding) |
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| pH | 7.4±n/a |
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| EC50 | 0.39±n/a nM |
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| Comments | extracted |
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| Citation |  Blumberg, LC; Deaver, D; Eyerman, D Morphan and morphinan analogues, and methods of use US Patent US9133125 Publication Date 9/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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|
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| BDBM179877 |
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| n/a |
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| Name | BDBM179877 |
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| Synonyms: | US10231963, Table B.23 | US10736890, Compound TABLE B.23 | US10752592, Compound TABLE B.5 | US11534436, Compound Table B.23 | US9133125, Table B, Compound 5 | US9656961, Example 00140 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N2O3 |
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| Mol. Mass. | 368.4693 |
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| SMILES | NC(=O)c1ccc2C[C@@H]3[C@@H]4CCC(=O)C[C@]4(CCN3CC3CCC3)c2c1O |r| |
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| Structure | 
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