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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2A | ||
| Ligand | BDBM180717 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| Ki | 2.45±n/a nM | ||
| Citation |  Gobbi, L; Jaeschke, G; Roche, O; Sarmiento, RM; Steward, L Dual modulators of 5HT2A and D3 receptors US Patent US8829029 Publication Date 9/9/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2A | |||
| Name: | 5-hydroxytryptamine receptor 2A | ||
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
| Type: | undefined | ||
| Mol. Mass.: | 52607.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28223 | ||
| Residue: | 471 | ||
| Sequence: |
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| BDBM180717 | |||
| n/a | |||
| Name | BDBM180717 | ||
| Synonyms: | US8829029, 17 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H35FN4O2 | ||
| Mol. Mass. | 514.6336 | ||
| SMILES | Fc1ccc2c(noc2c1)C1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2ccc(cc2)-n2cccc2)CC1 |r,wU:19.24,wD:16.17,(-4.69,-7.48,;-5.09,-5.99,;-4,-4.9,;-4.4,-3.41,;-5.89,-3.01,;-6.28,-1.53,;-7.77,-1.13,;-8.46,-3.7,;-6.97,-4.1,;-6.58,-5.59,;-5.19,-.44,;-3.71,-.84,;-2.62,.25,;-3.02,1.74,;-1.93,2.83,;-.44,2.43,;.65,3.52,;2.14,3.12,;3.22,4.21,;2.83,5.7,;1.34,6.1,;.25,5.01,;3.92,6.79,;5.4,6.39,;6.49,7.48,;5.8,4.9,;4.71,3.81,;5.11,2.32,;6.6,1.93,;7.69,3.01,;7.29,4.5,;7,.44,;8.46,-.04,;8.46,-1.58,;7,-2.05,;6.09,-.81,;-4.5,2.14,;-5.59,1.05,)| | ||
| Structure | 
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