Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | 5-hydroxytryptamine receptor 2A | ||
Ligand | BDBM180719 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
Ki | 2.257±n/a nM | ||
Citation | Gobbi, L; Jaeschke, G; Roche, O; Sarmiento, RM; Steward, L Dual modulators of 5HT2A and D3 receptors US Patent US8829029 Publication Date 9/9/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 2A | |||
Name: | 5-hydroxytryptamine receptor 2A | ||
Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
Type: | undefined | ||
Mol. Mass.: | 52607.65 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P28223 | ||
Residue: | 471 | ||
Sequence: |
| ||
BDBM180719 | |||
n/a | |||
Name | BDBM180719 | ||
Synonyms: | US8829029, 19 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H33F4N3O2 | ||
Mol. Mass. | 495.5527 | ||
SMILES | Fc1ccc2c(noc2c1)C1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2(CCC2)C(F)(F)F)CC1 |r,wU:19.24,wD:16.17,(-4.85,-7.48,;-5.25,-5.99,;-4.16,-4.9,;-4.56,-3.41,;-6.04,-3.01,;-6.44,-1.53,;-7.93,-1.13,;-8.62,-3.7,;-7.13,-4.1,;-6.73,-5.59,;-5.35,-.44,;-3.86,-.84,;-2.78,.25,;-3.17,1.74,;-2.09,2.83,;-.6,2.43,;.49,3.52,;1.98,3.12,;3.07,4.21,;2.67,5.7,;1.18,6.1,;.09,5.01,;3.76,6.79,;5.25,6.39,;6.33,7.48,;5.64,4.9,;4.87,3.57,;6.21,2.8,;6.98,4.13,;7.13,5.3,;8.62,5.7,;6.73,6.79,;7.53,3.81,;-4.66,2.14,;-5.75,1.05,)| | ||
Structure |