| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 3A4 |
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| Ligand | BDBM7885 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro ATRA 4-Hydroxylase Activity Assay |
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| pH | 7.4±n/a |
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| IC50 | 307500±n/a nM |
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| Comments | extracted |
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| Citation |  Bareja, SP; Jones, SD; Oblong, JE; Mills, KJ; Bierman, JC Cosmetic compositions containing substituted azole and methods for alleviating the signs of photoaged skin US Patent US9144538 Publication Date 9/29/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 3A4 |
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| Name: | Cytochrome P450 3A4 |
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| Synonyms: | Albendazole monooxygenase | Albendazole sulfoxidase | CP3A4_HUMAN | CYP3A3 | CYP3A4 | CYPIIIA3 | CYPIIIA4 | Cytochrome P450 3A3 | Cytochrome P450 3A4 (CYP3A4) | Cytochrome P450 HLp | Nifedipine oxidase | Quinine 3-monooxygenase | Taurochenodeoxycholate 6-alpha-hydroxylase |
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| Type: | Enzyme |
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| Mol. Mass.: | 57349.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 503 |
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| Sequence: | MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMF
DMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYS
MDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICV
FPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSI
IFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVV
NETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLG
GLLQPEKPVVLKVESRDGTVSGA
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| BDBM7885 |
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| n/a |
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| Name | BDBM7885 |
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| Synonyms: | 1-benzyl-2-methyl-1H-imidazole | US9138393, 1-benzyl-2-methylimidazole | US9144538, 1-benzyl-2-methylimidazole |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2 |
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| Mol. Mass. | 172.2264 |
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| SMILES | Cc1nccn1Cc1ccccc1 |
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| Structure | 
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