| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM183016 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7±n/a |
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| IC50 | 5±n/a nM |
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| Comments | extracted |
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| Citation |  Alet, N; Altenburger, J; Herault, J; Kirsch, R; Lassalle, G; Mallart, S; Philippo-Orts, M Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application US Patent US9150544 Publication Date 10/6/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
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| Type: | Enzyme |
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| Mol. Mass.: | 54726.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 488 |
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| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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| BDBM183016 |
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| n/a |
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| Name | BDBM183016 |
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| Synonyms: | US9150544, 50 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClN6O5S2 |
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| Mol. Mass. | 539.028 |
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| SMILES | CN(C)c1ncc(s1)S(=O)(=O)N[C@H]1CCN([C@H](Cc2cc3ccnc(N)c3cc2Cl)C(O)=O)C1=O |r| |
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| Structure | 
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