| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
|---|
| Ligand | BDBM86805 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| Ki | 0.073±n/a nM |
|---|
| Citation |  Carroll, FI; Ondachi, PW; Navarro, HA; Damaj, MI; Woods, JH; Jutkiewicz, EM Nicotinic receptor compounds US Patent US9150581 Publication Date 10/6/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
|---|
| Name: | Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
|---|
| Synonyms: | ACHA4_RAT | Acra4 | Chrna4 | Neuronal acetylcholine receptor subunit alpha 4 subtype | Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) | Neuronal acetylcholine receptor subunit alpha-4 beta 2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 70323.63 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P09483-2 |
|---|
| Residue: | 631 |
|---|
| Sequence: | MANSGTGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPS
PTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLF
MKRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSPAPTFCNPTDTAV
ETQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQ
EAAEDGIRCRSRSIQYCVSQDGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCKE
PSPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAM
VIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
|
|
|
|---|
| BDBM86805 |
|---|
| n/a |
|---|
| Name | BDBM86805 |
|---|
| Synonyms: | CAS_45263788 | NSC_45263788 | US9150581, RTI-7527-98 | rac-2-(5-(3-chlorophenyl)-6-fluoropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane hydrochloride |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H16ClFN2 |
|---|
| Mol. Mass. | 302.774 |
|---|
| SMILES | Fc1ncc(cc1-c1cccc(Cl)c1)C1CC2CCC1N2 |TLB:4:14:17.18:20| |
|---|
| Structure | 
|
|---|
Search and Browse
