| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
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| Ligand | BDBM50395220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 0.17±n/a nM |
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| Citation |  Carroll, FI; Ondachi, PW; Navarro, HA; Damaj, MI; Woods, JH; Jutkiewicz, EM Nicotinic receptor compounds US Patent US9150581 Publication Date 10/6/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
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| Name: | Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) |
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| Synonyms: | ACHA4_RAT | Acra4 | Chrna4 | Neuronal acetylcholine receptor subunit alpha 4 subtype | Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2) | Neuronal acetylcholine receptor subunit alpha-4 beta 2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 70323.63 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P09483-2 |
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| Residue: | 631 |
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| Sequence: | MANSGTGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPS
PTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLF
MKRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSPAPTFCNPTDTAV
ETQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQ
EAAEDGIRCRSRSIQYCVSQDGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCKE
PSPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAM
VIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
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| BDBM50395220 |
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| n/a |
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| Name | BDBM50395220 |
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| Synonyms: | CHEMBL2164664 | US9150581, RTI-7527-(+/-)-154 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19FN2O2S |
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| Mol. Mass. | 346.419 |
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| SMILES | CS(=O)(=O)c1ccc(cc1)-c1cc(cnc1F)C1CC2CCC1N2 |THB:12:17:20.21:23| |
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| Structure | 
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