| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesteryl ester transfer protein |
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| Ligand | BDBM184570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CETP In Vitro Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 11±n/a nM |
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| Comments | extracted |
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| Citation |  Trieselmann, T; Hamprecht, D; Wagner, H Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation US Patent US9150583 Publication Date 10/6/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesteryl ester transfer protein |
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| Name: | Cholesteryl ester transfer protein |
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| Synonyms: | CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I |
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| Type: | Enzyme |
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| Mol. Mass.: | 54751.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11597 |
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| Residue: | 493 |
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| Sequence: | MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
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| BDBM184570 |
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| n/a |
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| Name | BDBM184570 |
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| Synonyms: | US9150583, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H32F3NO5 |
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| Mol. Mass. | 519.5526 |
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| SMILES | COc1cc(ccc1C(F)(F)F)[C@H]1OC2(CCOCC2)c2c1c(nc1[C@H](O)C3(CC3)C[C@H](O)c21)C(C)C |r| |
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| Structure | 
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