| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Discoidin domain-containing receptor 2 |
|---|
| Ligand | BDBM185584 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Activity |
|---|
| IC50 | 5±n/a nM |
|---|
| Citation |  Bae, IH; Son, JB; Han, SM; Kwak, EJ; Kim, HS; Song, JY; Byun, EY; Jun, SA; Ahn, YG; Suh, KH Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases US Patent US9156852 Publication Date 10/13/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Discoidin domain-containing receptor 2 |
|---|
| Name: | Discoidin domain-containing receptor 2 |
|---|
| Synonyms: | DDR2 | DDR2_HUMAN | Discoidin domain receptor 2 (DDR2) | Discoidin domain-containing receptor 2 | Discoidin domain-containing receptor 2 (DDR2) | Epithelial discoidin domain-containing receptor 2 (DDR2) | NTRKR3 | TKT | TYRO10 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 96717.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q16832 |
|---|
| Residue: | 855 |
|---|
| Sequence: | MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
SFQEIHLLLLQQGDE
|
|
|
|---|
| BDBM185584 |
|---|
| n/a |
|---|
| Name | BDBM185584 |
|---|
| Synonyms: | US9156852, 1 | USRE47451, Example 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H17ClN6OS |
|---|
| Mol. Mass. | 460.939 |
|---|
| SMILES | Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1NC(=O)c1csc2c(N)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
