| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM185693 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Beta-Arrestin Recruitment (Tango) Assay |
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| pH | 7.4±n/a |
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| EC50 | 25±n/a nM |
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| Comments | extracted |
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| Citation |  Jin, J; Roth, B; Frye, S Functionally selective ligands of dopamine D2 receptors US Patent US9156822 Publication Date 10/13/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM185693 |
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| n/a |
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| Name | BDBM185693 |
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| Synonyms: | UNC10099988 | US9156822, 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22Cl2N4O2 |
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| Mol. Mass. | 421.32 |
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| SMILES | Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl |
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| Structure | 
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