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TargetD(2) dopamine receptor
LigandBDBM185696
Substrate/Competitorn/a
Meas. Tech.Beta-Arrestin Recruitment (Tango) Assay
pH7.4±n/a
EC50 1.5±n/a nM
Commentsextracted
Citation Jin JRoth BFrye S Functionally selective ligands of dopamine D2 receptors US Patent  US9156822 Publication Date 10/13/2015
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM185696
n/a
NameBDBM185696
Synonyms:UNC10108017 | US9156822, 40
TypeSmall organic molecule
Emp. Form.C25H31N3O4
Mol. Mass.437.5313
SMILESO=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2N1
Structure
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