Reaction Details |
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Target | 5-hydroxytryptamine receptor 2C |
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Ligand | BDBM50395587 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Radioligand Binding Assay |
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pH | 7.4±n/a |
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Ki | 115±n/a nM |
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Comments | extracted |
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Citation | Jin, J; Roth, B; Frye, S Functionally selective ligands of dopamine D2 receptors US Patent US9156822 Publication Date 10/13/2015 |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 2C |
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Name: | 5-hydroxytryptamine receptor 2C |
Synonyms: | 5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 51836.79 |
Organism: | Homo sapiens (Human) |
Description: | P28335 |
Residue: | 458 |
Sequence: | MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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BDBM50395587 |
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n/a |
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Name | BDBM50395587 |
Synonyms: | CHEMBL2165126 | UNC10000006 | US9156822, 2 |
Type | Small organic molecule |
Emp. Form. | C24H29Cl2N3O2 |
Mol. Mass. | 462.412 |
SMILES | Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl |
Structure |
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