| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium/glucose cotransporter 1 |
|---|
| Ligand | BDBM185702 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 65±0.0 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Kakinuma, H; Kobashi, Y; Chonan, T; Shiozawa, F; Iwata, Y; Oi, T; Kawabe, K 4-isopropyl-6-methoxyphenyl glucitol compound US Patent US9161945 Publication Date 10/20/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sodium/glucose cotransporter 1 |
|---|
| Name: | Sodium/glucose cotransporter 1 |
|---|
| Synonyms: | High affinity sodium-glucose cotransporter | NAGT | Na(+)/glucose cotransporter 1 | SC5A1_HUMAN | SGLT1 | SLC5A1 | Sodium-dependent glucose cotransporter 1 (SGLT1) | Sodium/glucose cotransporter 1 | Sodium/glucose cotransporter 1 (SGLT1) | Solute carrier family 5 member 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73503.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P13866 |
|---|
| Residue: | 664 |
|---|
| Sequence: | MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFL
AGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIY
IKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLA
IFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAI
PTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQR
CLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVG
CTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEK
ELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRV
NEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFIT
IVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKG
IFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCH
AYFA
|
|
|
|---|
| BDBM185702 |
|---|
| n/a |
|---|
| Name | BDBM185702 |
|---|
| Synonyms: | US9161945, (I) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H48N2O8 |
|---|
| Mol. Mass. | 612.7535 |
|---|
| SMILES | COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(N)=O)cc2C)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
