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TargetTransglutaminases (TGase)
LigandBDBM185768
Substrate/Competitorn/a
Meas. Tech.Enzyme Inhibition Assay
IC50 24000±5000 nM
Citation Pardin CKeillor JWLubell WD Cinnamoyl inhibitors of transglutaminase US Patent  US9162991 Publication Date 10/20/2015
More Info.:Get all data from this article,  Assay Method
 
Transglutaminases (TGase)
Name:Transglutaminases (TGase)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:77122.36
Organism:Cavia cutleri (Guinea pig)
Description:P08587
Residue:690
Sequence:
MAEDLILERCDLQLEVNGRDHRTADLCRERLVLRRGQPFWLTLHFEGRGYEAGVDTLTFN
AVTGPDPSEEAGTMARFSLSSAVEGGTWSASAVDQQDSTVSLLLSTPADAPIGLYRLSLE
ASTGYQGSSFVLGHFILLYNPRCPADAVYMDSDQERQEYVLTQQGFIYQGSAKFINGIPW
NFGQFEDGILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGR
WDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
FNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHCWVESWMTRPDLEPGYEGWQALDPT
PQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLV
VGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRI
RVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPF
SENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEP
KQNRKLIAEVSLKNPLPVPLLGCIFTVEGAGLTKDQKSVEVPDPVEAGEQAKVRVDLLPT
EVGLHKLVVNFECDKLKAVKGYRNVIIGPA
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  Blast E-value cutoff:
BDBM185768
n/a
NameBDBM185768
Synonyms:US9162991, 14b
TypeSmall organic molecule
Emp. Form.C15H10N4O4
Mol. Mass.310.2643
SMILES[O-]n1n[n+](C(=O)\C=C\c2cccc(c2)N(=O)=O)c2ccccc12
Structure
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