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TargetTransglutaminases (TGase)
LigandBDBM185773
Substrate/Competitorn/a
Meas. Tech.Enzyme Inhibition Assay
IC50>100000±n/a nM
Citation Pardin CKeillor JWLubell WD Cinnamoyl inhibitors of transglutaminase US Patent  US9162991 Publication Date 10/20/2015
More Info.:Get all data from this article,  Assay Method
 
Transglutaminases (TGase)
Name:Transglutaminases (TGase)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:77122.36
Organism:Cavia cutleri (Guinea pig)
Description:P08587
Residue:690
Sequence:
MAEDLILERCDLQLEVNGRDHRTADLCRERLVLRRGQPFWLTLHFEGRGYEAGVDTLTFN
AVTGPDPSEEAGTMARFSLSSAVEGGTWSASAVDQQDSTVSLLLSTPADAPIGLYRLSLE
ASTGYQGSSFVLGHFILLYNPRCPADAVYMDSDQERQEYVLTQQGFIYQGSAKFINGIPW
NFGQFEDGILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGR
WDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
FNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHCWVESWMTRPDLEPGYEGWQALDPT
PQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLV
VGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRI
RVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPF
SENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEP
KQNRKLIAEVSLKNPLPVPLLGCIFTVEGAGLTKDQKSVEVPDPVEAGEQAKVRVDLLPT
EVGLHKLVVNFECDKLKAVKGYRNVIIGPA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM185773
n/a
NameBDBM185773
Synonyms:US9162991, 15e
TypeSmall organic molecule
Emp. Form.C16H13N3O2
Mol. Mass.279.2933
SMILESCOc1cccc(\C=C\C(=O)n2nnc3ccccc23)c1
Structure
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