| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-glutamine gamma-glutamyltransferase 2 |
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| Ligand | BDBM185761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| IC50 | 11000±1500 nM |
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| Citation |  Pardin, C; Keillor, JW; Lubell, WD Cinnamoyl inhibitors of transglutaminase US Patent US9162991 Publication Date 10/20/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-glutamine gamma-glutamyltransferase 2 |
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| Name: | Protein-glutamine gamma-glutamyltransferase 2 |
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| Synonyms: | TGM2 | TGM2_CAVCU | Transglutaminases (TGase) |
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| Type: | Enzyme |
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| Mol. Mass.: | 77122.36 |
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| Organism: | Cavia cutleri (Guinea pig) |
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| Description: | P08587 |
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| Residue: | 690 |
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| Sequence: | MAEDLILERCDLQLEVNGRDHRTADLCRERLVLRRGQPFWLTLHFEGRGYEAGVDTLTFN
AVTGPDPSEEAGTMARFSLSSAVEGGTWSASAVDQQDSTVSLLLSTPADAPIGLYRLSLE
ASTGYQGSSFVLGHFILLYNPRCPADAVYMDSDQERQEYVLTQQGFIYQGSAKFINGIPW
NFGQFEDGILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGR
WDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
FNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHCWVESWMTRPDLEPGYEGWQALDPT
PQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLV
VGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRI
RVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPF
SENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEP
KQNRKLIAEVSLKNPLPVPLLGCIFTVEGAGLTKDQKSVEVPDPVEAGEQAKVRVDLLPT
EVGLHKLVVNFECDKLKAVKGYRNVIIGPA
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| BDBM185761 |
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| n/a |
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| Name | BDBM185761 |
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| Synonyms: | US9162991, 4f |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4O3 |
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| Mol. Mass. | 340.3764 |
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| SMILES | O=C(\C=C\c1ccc(cc1)N(=O)=O)c1cn(CC2CCCCC2)nn1 |
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| Structure | 
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