Ki Summary

Reaction Details

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Target

Cell division cycle 7-related protein kinase

Ligand

BDBM50337330

Substrate/Competitor

n/a

Meas. Tech.

Inhibition Assay

7.5±n/a

56.3±n/a nM

Comments

extracted

Citation

Akritopoulou-Zanze, I; Wakefield, BD; Mack, H; Turner, SC; Gasiecki, AF; Gracias, VJ; Sarris, KA; Kalvin, DM; Michmerhuizen, MJ; Shuai, Q; Patel, JR; Bakker, MH; Teusch, N; Johnson, EF; Kovar, PJ; Djuric, SW; Long, AJ; Vasudevan, A; George, DM; Wang, L; Li, B; Moore, NS; Hobson, AD; Woods, KW; Miyashiro, JM; Swann, Jr., SL; Penning, TD 5-substituted indazoles as kinase inhibitors US Patent US9163007 Publication Date 10/20/2015

More Info.:

Get all data from this article, Assay Method

Cell division cycle 7-related protein kinase

Name:

Cell division cycle 7-related protein kinase

Synonyms:

Type:

Protein

Mol. Mass.:

63908.16

Organism:

Homo sapiens (Human)

Description:

O00311

Residue:

574

Sequence:

MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKI
EDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGV
KYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKP
SNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG
PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVC
SICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDD
LTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQ
GHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPD
EAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL

BDBM50337330

n/a

Name

BDBM50337330

Synonyms:

5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682352 | US9163007, 10

Type

Small organic molecule

Emp. Form.

C16H12FN5

Mol. Mass.

293.2984

SMILES

Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1

Structure