| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydrolipoyl dehydrogenase |
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| Ligand | BDBM36527 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7±n/a |
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| IC50 | <40±n/a nM |
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| Comments | extracted |
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| Citation |  Wong, C; Wu, Y Compounds and methods for treating tuberculosis infection US Patent US9073941 Publication Date 7/7/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydrolipoyl dehydrogenase |
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| Name: | Dihydrolipoyl dehydrogenase |
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| Synonyms: | DLDH_MYCTU | Lipoamide Dehydrogenase (Lpd) | lpd | lpdC |
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| Type: | Enzyme |
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| Mol. Mass.: | 49231.98 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WHH9 |
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| Residue: | 464 |
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| Sequence: | MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH
IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT
LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG
AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD
GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN
VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL
TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL
PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF
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| BDBM36527 |
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| n/a |
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| Name | BDBM36527 |
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| Synonyms: | 1,6-dimethyl-3-phenyl-1H,5H,6H,7H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione, 10 | US9073941, 601 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11N5O2 |
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| Mol. Mass. | 269.2587 |
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| SMILES | Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 |
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| Structure | 
|
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